Microbiological findings and host response in patients with peri-implantitis.
Identifieur interne : 008218 ( Main/Exploration ); précédent : 008217; suivant : 008219Microbiological findings and host response in patients with peri-implantitis.
Auteurs : Margareta Hultin [Suède] ; Anders Gustafsson ; Hadar Hallström ; L-A Johansson ; Anders Ekfeldt ; Björn KlingeSource :
- Clinical oral implants research [ 0905-7161 ] ; 2002.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Aggregatibacter actinomycetemcomitans (isolement et purification), Bacteroides (isolement et purification), Exsudat gingival (), Exsudat gingival (microbiologie), Femelle, Gingivite (), Gingivite (microbiologie), Humains, Implants dentaires (microbiologie), Indice de plaque dentaire, Indice parodontal, Interleukine-1 (analyse), Lactoferrine (analyse), Mâchoire partiellement édentée (), Mâchoire partiellement édentée (microbiologie), Mâle, Pancreatic elastase (analyse), Parodontite (microbiologie), Parodontite (métabolisme), Poche parodontale (), Poche parodontale (microbiologie), Porphyromonas gingivalis (isolement et purification), Prevotella intermedia (isolement et purification), Résorption alvéolaire (), Résorption alvéolaire (microbiologie), Statistique non paramétrique, Sujet âgé, Treponema (isolement et purification).
- MESH :
- analyse : Interleukine-1, Lactoferrine, Pancreatic elastase.
- isolement et purification : Aggregatibacter actinomycetemcomitans, Bacteroides, Porphyromonas gingivalis, Prevotella intermedia, Treponema.
- microbiologie : Exsudat gingival, Gingivite, Implants dentaires, Mâchoire partiellement édentée, Parodontite, Poche parodontale, Résorption alvéolaire.
- métabolisme : Parodontite.
- Adulte d'âge moyen, Exsudat gingival, Femelle, Gingivite, Humains, Indice de plaque dentaire, Indice parodontal, Mâchoire partiellement édentée, Mâle, Poche parodontale, Résorption alvéolaire, Statistique non paramétrique, Sujet âgé.
English descriptors
- KwdEn :
- Aged, Aggregatibacter actinomycetemcomitans (isolation & purification), Alveolar Bone Loss (classification), Alveolar Bone Loss (microbiology), Bacteroides (isolation & purification), Dental Implants (microbiology), Dental Plaque Index, Female, Gingival Crevicular Fluid (chemistry), Gingival Crevicular Fluid (microbiology), Gingivitis (classification), Gingivitis (microbiology), Humans, Interleukin-1 (analysis), Jaw, Edentulous, Partially (microbiology), Jaw, Edentulous, Partially (surgery), Lactoferrin (analysis), Male, Middle Aged, Pancreatic Elastase (analysis), Periodontal Index, Periodontal Pocket (classification), Periodontal Pocket (microbiology), Periodontitis (metabolism), Periodontitis (microbiology), Porphyromonas gingivalis (isolation & purification), Prevotella intermedia (isolation & purification), Statistics, Nonparametric, Treponema (isolation & purification).
- MESH :
- chemical , analysis : Interleukin-1, Lactoferrin, Pancreatic Elastase.
- chemical , microbiology : Dental Implants.
- chemistry : Gingival Crevicular Fluid.
- classification : Alveolar Bone Loss, Gingivitis, Periodontal Pocket.
- isolation & purification : Aggregatibacter actinomycetemcomitans, Bacteroides, Porphyromonas gingivalis, Prevotella intermedia, Treponema.
- metabolism : Periodontitis.
- microbiology : Alveolar Bone Loss, Gingival Crevicular Fluid, Gingivitis, Jaw, Edentulous, Partially, Periodontal Pocket, Periodontitis.
- surgery : Jaw, Edentulous, Partially.
- Aged, Dental Plaque Index, Female, Humans, Male, Middle Aged, Periodontal Index, Statistics, Nonparametric.
Abstract
The aim of the present study was to characterise microbiota and inflammatory host response around implants and teeth in patients with peri-implantitis. We included 17 partly edentulous patients with a total of 98 implants, of which 45 showed marginal bone loss of more than three fixture threads after the first year of loading. Nineteen subjects with stable marginal tissue conditions served as controls. Oral hygiene, gingival inflammation, and probing pocket depth were evaluated clinically at teeth and implants. Microbiological and crevicular fluid samples were collected from five categories of sites: 1) implants with peri-implantitis (PI), 2) stable implants (SI) in patients with both stable and peri-implantitis implants, 3) control implants (CI) in patients with stable implants alone, 4) teeth in patients (TP) and 5) controls (TC). Crevicular fluid from teeth and implants was analysed for elastase activity, lactoferrin and IL-1 beta concentrations. Elastase activity was higher at PI than at CI in controls. Lactoferrin concentration was higher at PI than at SI in patients with peri-implantitis. Higher levels of both lactoferrin and elastase activity were found at PI than at teeth in patients. The concentrations of IL-1 beta were about the same in the various sites. Microbiological DNA-probe analysis revealed a putative periodontal microflora at teeth and implants in patients and controls. Patients with peri-implantitis harboured high levels of periodontal pathogens, Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Bacteroides forsythus and Treponema denticola. These findings indicate a site-specific inflammation rather than a patient-associated specific host response.
PubMed: 12175371
Affiliations:
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Le document en format XML
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(analysis)</term><term>Male</term><term>Middle Aged</term><term>Pancreatic Elastase (analysis)</term><term>Periodontal Index</term><term>Periodontal Pocket (classification)</term><term>Periodontal Pocket (microbiology)</term><term>Periodontitis (metabolism)</term><term>Periodontitis (microbiology)</term><term>Porphyromonas gingivalis (isolation & purification)</term><term>Prevotella intermedia (isolation & purification)</term><term>Statistics, Nonparametric</term><term>Treponema (isolation & purification)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Aggregatibacter actinomycetemcomitans (isolement et purification)</term><term>Bacteroides (isolement et purification)</term><term>Exsudat gingival ()</term><term>Exsudat gingival (microbiologie)</term><term>Femelle</term><term>Gingivite ()</term><term>Gingivite (microbiologie)</term><term>Humains</term><term>Implants dentaires (microbiologie)</term><term>Indice de plaque dentaire</term><term>Indice parodontal</term><term>Interleukine-1 (analyse)</term><term>Lactoferrine (analyse)</term><term>Mâchoire partiellement édentée ()</term><term>Mâchoire partiellement édentée (microbiologie)</term><term>Mâle</term><term>Pancreatic elastase (analyse)</term><term>Parodontite (microbiologie)</term><term>Parodontite (métabolisme)</term><term>Poche parodontale ()</term><term>Poche parodontale (microbiologie)</term><term>Porphyromonas gingivalis (isolement et purification)</term><term>Prevotella intermedia (isolement et purification)</term><term>Résorption alvéolaire ()</term><term>Résorption alvéolaire (microbiologie)</term><term>Statistique non paramétrique</term><term>Sujet âgé</term><term>Treponema (isolement et purification)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Interleukin-1</term><term>Lactoferrin</term><term>Pancreatic Elastase</term></keywords><keywords scheme="MESH" type="chemical" 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Index</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Periodontal Index</term><term>Statistics, Nonparametric</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Exsudat gingival</term><term>Femelle</term><term>Gingivite</term><term>Humains</term><term>Indice de plaque dentaire</term><term>Indice parodontal</term><term>Mâchoire partiellement édentée</term><term>Mâle</term><term>Poche parodontale</term><term>Résorption alvéolaire</term><term>Statistique non paramétrique</term><term>Sujet âgé</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The aim of the present study was to characterise microbiota and inflammatory host response around implants and teeth in patients with peri-implantitis. We included 17 partly edentulous patients with a total of 98 implants, of which 45 showed marginal bone loss of more than three fixture threads after the first year of loading. Nineteen subjects with stable marginal tissue conditions served as controls. Oral hygiene, gingival inflammation, and probing pocket depth were evaluated clinically at teeth and implants. Microbiological and crevicular fluid samples were collected from five categories of sites: 1) implants with peri-implantitis (PI), 2) stable implants (SI) in patients with both stable and peri-implantitis implants, 3) control implants (CI) in patients with stable implants alone, 4) teeth in patients (TP) and 5) controls (TC). Crevicular fluid from teeth and implants was analysed for elastase activity, lactoferrin and IL-1 beta concentrations. Elastase activity was higher at PI than at CI in controls. Lactoferrin concentration was higher at PI than at SI in patients with peri-implantitis. Higher levels of both lactoferrin and elastase activity were found at PI than at teeth in patients. The concentrations of IL-1 beta were about the same in the various sites. Microbiological DNA-probe analysis revealed a putative periodontal microflora at teeth and implants in patients and controls. Patients with peri-implantitis harboured high levels of periodontal pathogens, Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Bacteroides forsythus and Treponema denticola. These findings indicate a site-specific inflammation rather than a patient-associated specific host response.</div></front></TEI><affiliations><list><country><li>Suède</li></country></list><tree><noCountry><name sortKey="Ekfeldt, Anders" sort="Ekfeldt, Anders" uniqKey="Ekfeldt A" first="Anders" last="Ekfeldt">Anders Ekfeldt</name><name sortKey="Gustafsson, Anders" sort="Gustafsson, Anders" uniqKey="Gustafsson A" first="Anders" last="Gustafsson">Anders Gustafsson</name><name sortKey="Hallstrom, Hadar" sort="Hallstrom, Hadar" uniqKey="Hallstrom H" first="Hadar" last="Hallström">Hadar Hallström</name><name sortKey="Johansson, L A" sort="Johansson, L A" uniqKey="Johansson L" first="L-A" last="Johansson">L-A Johansson</name><name sortKey="Klinge, Bjorn" sort="Klinge, Bjorn" uniqKey="Klinge B" first="Björn" last="Klinge">Björn Klinge</name></noCountry><country name="Suède"><noRegion><name sortKey="Hultin, Margareta" sort="Hultin, Margareta" uniqKey="Hultin M" first="Margareta" last="Hultin">Margareta Hultin</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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